Mobinur Rehman, Ishaque Shaikh, Shams Ullah Bazai, Aneela Shaheen.
Frequency and Susceptibility of Organisms Causing Neonatal Sepsis.
Pak J Med Health Sci Jan ;6(4):976-8.

Objective: To determine the frequency and susceptibility of organism of bacterial agents responsible for neonatal sepsis. Patients and methods: This cross-sectional descriptive study included 209 patients and done in Nursery Bolan Medical Complex Hospital Quetta between July 2012 to December 2012. The patients any indicative of sepsis like drowsiness, refusal to feed, respiratory distress, temperature instability, cyanosis, seizure or neonates born to mother with maternal peripartum fever 38°C, premature rupture of membranes >18 hours, foul smelling or meconium stained liquor or frequent >3 unclear vaginal examinations were included. The neonates with major congenital anomalies like spina bifida, cleft palate, Down’s syndrome were excluded. Results: The mean age of the patients was 10.3 days and male to female ratio was 1.1:1. The significant symptoms were poor feeding which was present in 88.5%, lethargy in 83.3%. The frequency of organisms isolated in blood culture was Pseudomonas 29.7%, Klebsiella 10.5%, E Coli 18.7%, Staph Aureus 29.2%, Enterococcus 16.4% and Streptococcus Pneumoniae 2.4%. Conclusion: The spectrum and susceptibility of organism causing neonatal sepsis is changing and physicians ought to remain on guard.

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