Aydin Tasdogen, Yuksel Erkin, Leylaseden Duru, Edip Gonullu.
Effects of line type blood-liquid warmer on two different infusion sets.
J Pak Med Assoc Jan ;65(4):362-5.

Objective: To investigate the source of 'bubbles' in infusion sets which were caused by the 'line type' blood-liquid warmers used in operation rooms to prevent hypothermia. Methods: The experimental study was conducted from August to September 2012 at the Thoracic Surgery Department of Dokuz Eylul University, Izmir, Turkey, by warming liquids in the operation room experimentally in a setting similar to clinical routine. Initially, 0.9% sodium chloride solution was infused using S-line blood-liquid warmers with Medisetin patients who were placed in Group M). The IPC Group had Intrafix Primeline Confortset at a rate of 350ml/hour in the operating room. The initiation time and level of bubble formation, temperatures of the operation room, infusion liquid, S-line device, line of the device, and the liquid at the outflow were recorded. Data was analysed with SPSS 15. Result: The two groups had 10 subjects each. The temperatures of the working area, the liquid before and after being placed in the warming device, the proximal-middle and distal parts of the line and the set temperature on the screen of the device were similar and the difference between them was not statistically significant (p>0.05). While no bubble formation was observed in Group IPC, bubbles were formed after 9.80±0.78 minutes and the level of bubble formation was close to 3 in Group Mediset (2.80±1.03). The main difference between the two groups was di (2-ethylhexyl) phthalate content of Mediset. Conclusion: Infusion sets containing di(2-ethylhexyl) phthalate should not be used with warming devices in order to avoid toxic effects.

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