Qazi Jalaluddin Ahmed, Sunil Dutt Suchdev, Hashim, Ali Hasan, Sarfaraz.
Use of Prophylactic Antibiotics in Inguinal Hernia Repair: A Randomized Study in Tertiary care hospital Karachi.
Pak J Surg Jan ;30(4):306-9.

Objective: To detect the use of prophylactic antibiotics in inguinal hernia repair. Design: Prospective study. Sett ing and duration: KVSS SITE Hospital, Karachi from January 2012 to December 2012 Methodology: A total of two hundred patients were included that underwent inguinal hernia repair at KVSS SITE Hospital, Karachi during the period. Th ey were randomized in two groups. Group 1 was given prophylactic dose of injamoxi-clav while group 2 was given placebo only. Results were compared and Data analyzed using the Chi-square test. Complications in both the groups were compared. Results: Rate of serous discharge and seroma formation was 1% and 22% respectively in group 1 while 2% and 26% in group 2 also the rate of erythema and stitch abscess were 1% and none in group 1 and 2% and 1% in group 2 respectively. On statistical analysis these diff erences were not signifi cant. Conclusion: Prophylactic antibiotics in elective inguinal hernia repair have no substantial advantage over placebo although more studies are essential to prepare someAddition of prophylactic antibiotics in elective open inguinal hernia repair has no signifi cant benefi t over placebo although larger studies are required to prepare some uniform guidelines. guidelines.

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