Maryam Mukhtar, Sajad Khan, Altaf Ahmed.
ACINETOBACTER : An emerging enemy in tertiary care hospital.
Infect Dis J Jan ;22(1):532-5.

Acinetobacter species is a rapidly spreading nosocomial pathogen. Clinical isolates of this genus are often resistant to multiple antibiotics. Thus this study was conducted to analyze antimicrobial susceptibility pattern and frequency of Acinetobacter spp. in hospitalized and outpatients in our set up. Methods: A total of 232 Acinetobacter isolates obtained from various clinical specimens submitted to Indus Hospital diagnostic laboratory from January 2008 to September 2012 were included. Isolates were identified and antibiotic sensitivities were performed using standard microbiological procedures. Results: Acinetobacter spp was isolated in 232 samples out of 10190 gram negative isolates (2.3% prevalence) from the entire hospital. 72 % were isolated from hospitalized patients. Overall sensitivities of Acinetobacter spp against Polymyxin B, Tobramycin, Tigecycline, Meropenem, Imipenem, Cefoperazone/sulbactam, Amikacin, Ceftazidime, Ciprofloxacin, Cefotaxime, Piperacillin – tazobactam and Co-trimoxazole were 88.5%, 84%, 67.2%, 54.6%, 54.6%, 53.6%, 47.4%, 41.2%, 39.2%, 34.1%, 34% and 30.6% respectively. 21 (9%) isolates were detected as multidrug resistant. Conclusion: Acinetobacter spp especially drug resistant is a great concern of limiting the therapeutic options.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals -