Hammad Azam, Ghulam Hussain, Naseem Ahmed, Mirza Ahmad Raza Baig, Syed Raffay Ali Gilani, Sara Zaheer.
Comparison of semi-continuous and interrupted suture techniques for mitral valve replacement.
J Pak Med Assoc Jan ;65(8):844-6.

Objectives: To compare the efficacy of semi-continuous technique and interrupted suture technique for mitral valve replacement in early post-operative period. Method: The randomised prospective study was conducted at Chaudhry Pervaiz Elahi Institute of Cardiology, Multan, Pakistan, from December 2012 to December 2014 The patients were divided into two equal groups: Group I patients underwent semi-continuous technique for mitral valve replacement, and Group II underwent interrupted technique. Data was analysed using SPSS 16. Results: The 100 patients were divided into two equal groups of 50(50%) each. There was no significant difference in terms of age, gender and pre-operative echocardiographic characteristics (p>0.05 each). Total bypass and cross-clamp times were significantly higher in Group II (p<0.0001 and p<0.0001). The incidence of peri-prosthetic leakage was low in Group II compared to Group I but it was not significantly different (p=0.64). Conclusions: Semi-continuous technique was found to be a safe and reliable method of mitral valve replacement.

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