Muhammad Jaseem Khan, Basir Ahmed, Momin Khan, Saeed Ahmed.
Increase in serum alkaline phosphatase due to fatty meal in undergraduate students of Khyber Medical University, Khyber Pakhtunkhwa.
J Pak Med Assoc Jan ;66(4):378-9.

Objective: To evaluate the effect of fatty meal on intestinal alkaline phosphatase. Methods: The cross-sectional study was conducted at Khyber Medical University, Peshawar, Pakistan from March to April 2014 and comprised young healthy individuals 18-25 years of age. Whole blood samples were collected from the subjects in ethylenediaminetetraacetic acid anti-coagulated and plane serum tubes. For blood group analysis, blood group anti sera were used, while for serum alkaline phosphatase, a chemistry analyser was used. Alkaline phosphatase levels in the blood before and after breakfast were compared. Results: Of the 177 subjects, there were 139(78.5%) men and 38(21.4%) women. Mean fasting alkaline phosphatise level was 144.22+/-75.57, while mean random value was 174.15+/-96.70 (p=0.001). Conclusion: Serum alkaline phosphatise must be analysed in fasting state early in the morning.

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