Muhammad Wajih Uddin Butt, Muhammad Amer Mian, Naveed Ahmed, Umar Bin Abdul Aziz, Wasif Idris Ahmed, Syed Adeel Ahmed, Salman Arif.
Comparison of frequency of recurrence following aspiration and injection of steroid versus surgical excision in the treatment of wrist ganglion.
Pak Armed Forces Med J Jan ;64(3):428-31.

Objective: To compare the frequency of recurrence following aspiration and injection of steroid versus surgical excision in the treatment of wrist ganglion. Study Design: Randomized controlled trial. Place and Duration of Study: General surgical department, Combined Military Hospital, Rawalpindi, Pakistan, from Jan 2010 to Dec 2010. Material and Methods: Sixty patients of clinically diagnosed wrist ganglia were randomized into groups ‘A’ and ‘B’ with 30 patients in each group. After approval by the hospital ethical committee, patients in group ‘A’ were subjected to aspiration and injection of methyl-prednisolone acetate 40 mg/ml and those in group ‘B’ underwent surgical excision of the ganglion. Patients were explained the procedure they were subjected to and they were also counselled about the risk of recurrence after a particular procedure and after that informed written consent was obtained from them. Patients were followed up at intervals of 2 weeks, 6 weeks, 3 months and 6 months after the procedure to look for recurrence in both groups. Results: On follow up at 6 months, 12 (40%) patients in group A while only 2 (6.66%) patients in group B had recurrence of the ganglion. No complications were noted. This difference was found to be statistically significant (p = 0.0023). Conclusion: Recurrence of wrist ganglion is considerably less in patients treated with surgical excision and should be preferred over aspiration and steroid injection.

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