Ziauddin A Kashmiri, Umair-ul Islam, Santosh Kumar.
Effect of intrathecal fentanyl on duration of post operative analgesia. A Comparison between inj. bupivacaine with inj. fentanyl and inj. bupivacine alone, in elective lower abdominal and lower limb orthopaedic surgeries.
Pak J Surg Jan ;31(3):161-4.

Objective: To study the eff ect of Intrathecal fentanyl on the duration of post operative analgesia and compare inj. bupivacaine with inj. fentanyl and inj. bupivacine alone. Design: Th is was a prospective double blinded randomized controlled trial Sett ing and Duration: Th is study carried out from September 2013 to March 2014 at the Civil Hospital, Dow University of Health Sciences, Karachi. Methodology: Th is study was conducted on 60 patients who were divided in to 2 groups, each group containing 30 patients. Group BF received hyperbaric inj. 0.5 % bupivacaine (3ml - 15 m.g. + 0.5 m.l. fentanyl 25 μg). Group BN received hyperbaric bupivacaine 0.5 % (3ml – 15mg & 0.5 ml Normal Saline). Result: Duration of postoperative (PO) analgesia was signifi cantly longer in BF group as compare to BN group ( 249.87 ± 32.59 vs 161.97 ± 25.55). (P= 0.0005) Conclusion: Th is study concludes that giving fentanyl along with Bupivacanine increases the duration of post operative analgesia as compare to bupivacaine alone.

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