Atif Nazir, Abdul Rehman Abid, Tahir Abbas Shah, Habib Afzal, Naresh Kumar, Muhammad Saleem.
Gender impact on in-hospital outcome after percutaneous coronary intervention.
J Cardiovascular Dis Jan ;10(2):33-8.

Objective: Objective: To compare in-hospital complications between males and females after percutaneous coronary Objective: intervention (PCI). Materials and Methods: Materials and Methods: This Cohort study was conducted at the Coronary Care Unit and Angiography Materials and Methods: Department of the Punjab Institute of Cardiology, Lahore from January to June 2010. Non-probability, purposive sampling technique was used. A total of 1243 percutaneous coronary interventions were done. Out of these 1050 patients, were selected. All the baseline procedural and biochemical characteristics were recorded. All patients were evaluated for cumulative vascular complications (access site hematoma, psuedoaneurysm, retroperitoneal bleed and blood transfusion requirements) and contrast induced nephropathy. Results: Results: Out of 1050 cases, (525 were males and 525 females). In terms of gender related risk, cumulative vascular complications (CVC) were significantly more often seen in females as compared to males, 48(9.14%) vs 25(4.76%) respectively (p <0.005). Out of these CVC, access site hematoma was present in 31(5.90%) females as compared to 18(3.42%) males. Blood transfusion was required in 16(3.04%) females and 06(1.14%) males. There was no significant gender differences in contrast induced nephropathy, 14(2.66%) females vs 9(1.71%) males. Conclusion: Conclusion: Women are at increased risk of cumulative vascular complications as compared to men but Conclusion: the complication of contrast induced nephropathy was similar in men and women. Key words: ey words: Percutaneous coronary intervention, gender differences, vascular complications, contrast ey words: induced nephroparhy, major adverse cardiovascular events.

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