Tajammal Abbas Shah.
Cleft lip and palate; prevalence, patients presenting to a surgical ward at Allied hospital Faisalabad, in one year.
Professional Med J Jan ;23(05):516-21.

A prospective study was conducted to look for prevalence of cleft lip and palate in a population presenting to a surgical unit in a teaching hospital. Objectives: To see prevalence of cleft lip and palate alone, lip and palate combined, right or left sided, male to female distribution, and possible factors responsible for clefting. Study Design: A prospective study. Setting: Surgical Unit II at Allied Hospital Faisalabad. Period: March 2009 to March 2010 for one year. Materials and Methods: Total 55 patients were treated in year 2009 out of total 17900 (0.3 %) patients admitted in all surgical wards and 6508 patients admitted in surgical unit II (0.8%). Patients were divided into three groups, cleft lip alone (group A), cleft palate alone (group B) and combined cleft lip and palate (group C). Children up to the age of 5 years with congenital abnormality were included in study. Results: Out of 6508 patients admitted in surgical unit II 55 patients (0.8%) had cleft lip and palate defect. 55 patients were divided in three groups. In group A, 32 patients presented with cleft lip alone ( 58.1 % ), 16 ( 29 % ) were males and 16 ( 29 % ) were females, 21 patients have left sided ( 38 % ), 4 right sided (7.27% ) and 7 patients have bilateral ( 12.72 % ) defects. 2 patients (3.63 %) had family history of cleft lip and both were males. In group B, 12 patients ( 21.8 %) had cleft palate alone, 7 patients ( 12.72 % ) were males and 5 patients ( 9 % ) were females, 10 patients ( 1.18 % ) had soft palate only while 2 patients ( 3.63 % ) had compete ( hard and soft ) palatal defect. In group C, 11 patients, had cleft lip and palate combined ( 20 % ), 6 patients were males ( 10.9 % ) and 5 patients ( 9 % ) were females, 8 patients ( 14.54 % ) had only soft palate defect while 3 patients ( 5.45 % ) had complete palatal defect associated with 8 patients ( 14.54 % ) left sided unilateral lip defect and 3 patients ( 5.45% ) had bilateral cleft lip. All patients were operated without any mortality. Ages of mothers at earliest were 16 and 18 years, 3 cousin marriages, ( 5.45 % ) all fathers were smokers, belonged to poor socio economic families and no history of mother’s exposure to radiation, drug abuse during gestational life. Conclusion: As it is obvious from this study that all patients belongs to poor socio economics group, and all fathers were smokers, 3 patients born in parents who had cousin marriages ( 5.45 % ) 2 patients ( 3.63 % ) with family history, cleft lip and palate are multifactorial congenital abnormalities, runs in families and is influenced by various environmental factors.

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