Asif Hussain Munir, Saima Nadeem, Amina, Zahid Ashraf.
Effects of benign and malignant tertian malaria on hematological findings.
J Med Sci Jan ;23(3):141-5.

Objective: To find out different changes in the peripheral blood of patients suffering from Malaria. Material and Methods: It was a descriptive case series study conducted in pathology department of KMC/KTH from May 2013 to May 2014. A total of 200 Malarial patients were subjected to complete blood counts performed in automated Haematology analyzer, Sysmex KX 21 and thick and thin blood films stained with Giemsa to confirm Malarial parasite. Results: Out of 200, 60% were male and 40% were female. Plasmodium Vivax was found in 68% and Plasmodium Falciparum in 32% cases. Automated Haematology Analyzer results showed that minimum total Leucocyte Count was 1100/cmm, maximum was 25,200/cmm, minimum haemoglobin was 2.50 g/dl, minimum platelet count was 10,000, maximum 4,03,00/cmm. Anemia was recorded in 51%; thrombocytopenia was recorded in 51% cases. TLC was normal in 82% of the cases while leukopenia was found in 08% and lecocytosis in 20% of the total patients. Pancytopenia observed in 03% cases. Conclusion: Incidence of malaria is higher in plain areas, males were more prone than females. The Haematological findings in descending order was, Thrombocytopenia, leucopoenia and pancytopenia.

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