Radhia Khan, Khurshid Ali, Zakkia Khan, Safdarhussain Shah, Nawabzada, Mohammad Shoaib Khan.
Cinnamon on the Functions of Liver and Kidney in Type 2 Diabetic Individuals.
Ann Pak Inst Med Sci Jan ;8(2):145-9.

Objective: The objectives of this study were to know the effect of cinnamon on liver functions tests i.e. alanine transferase, alkaline phosphatase, bilirubin and on the renal function tests i.e. urea and creatinine in type 2 diabetic individuals. Place and Duration: The study was conducted during the year 2007-2009 in the Institute of Biotechnology and Genetic Engineering, NWFP, Agricultural University Peshawar and Diabetic Hospital of Abbasin Institute of Medical Sciences, Peshawar, Pakistan. Study Design:Randomized Complete Block Design (RCBD) was implemented, and two- way analysis of variance was used for statistical analysis. Materials and Methods: Fourteen diabetic individuals of both sexes and of age 40 years and above were divided into two groups, each having 7 individuals. Group 1 was assigned for 1.5g cinnamon dose/day while group 2 was assigned for 1.5g placebo dose/day. Fasting blood samples were collected before starting the experiment (day 0) and at the end of the experiment (day 30) from both the cinnamon and placebo groups. Serum was separated and liver function tests namely, alanine amino transferase (ALT), alkaline phosphates (ALP), and bilirubin and renal function tests namely urea and creatinine of both groups 1 and 2 were determined by standard kit methods. Results: ALT, ALP and Bilirubin concentration of type 2 diabetic individuals of the cinnamon and placebo groups were not changed and the values were in the normal range. Similarly urea and creatinine concentration of the type 2 diabetic individuals of the cinnamon and placebo groups were not changed and the values were in the normal range. The results indicated that cinnamon dose is not affecting the functions of liver and kidney. Conclusion: Cinnamon intake may not affect the liver and renal functions in type 2 diabetic individuals and its intake may be safe and the diabetic individuals may use it for longer time for their sugar control.

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