Rizwan Aziz Qazi, Naila Bashir, Yousaf Daud.
Correlation of CD4 Lymphocyte Count with Haemoglobin Concentration in HIV Infected Patients at HIV Treatment Center P.I.M.S Islamabad.
Ann Pak Inst Med Sci Jan ;9(3):138-40.

Objectives: To find correlation between CD4 lymphocyte count and heamoglobin concentration in HIV infected patients. Study Design: Descriptive observational study. Place and Duration: HIV/AIDS treatment center Pakistan institute of medical sciences, Islamabad. The study was conducted between march 2013 to September 2013 Materials and Methods: Two hundred and ninety nine (299) HIV positive patients were enrolled in this study .Blood CP and CD4 counts were done as a part of baseline investigations. Hemoglobin concentration and CD4 counts were analyzed in all the patients and their correlation assessed. Results: The mean blood hemoglobin concentration in 299 patients was (12.56+1.86) with minimum hemoglobin concentration of (6.7g/dl) and maximum of (17.6g/dl).Mean CD4 count was (475.89+286.76) with minimum CD4 count of (11) and maximum of (1464).Using the persons correlation there was a significant and positive correlation between hemoglobin concentration and CD4 count. (r2=0.023 and p=0.009) at 0.01 level one tailed. Conclusions: Anemia in HIV patients is associated with increased morbidity and mortality. Hemoglobin concentration in HIV patients depends on several factors such as co morbidities, use of ARVs etc. Our study shows that CD4 count is an important determinant of hemoglobin concentration and low hemoglobin counts portends a bad prognosis in HIV patients as they are positively correlated with patients’ immune status.

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