Salman Waris, Muhammad Yousuf, Rana Altaf Ahmed, Aftab Haider.
Isoflurane versus Halothane for induction and maintenance of Anesthesia in Children.
J Surg Pak Jan ;7(2):2-5.

Forty un premedicated children undergoing adenoidectomy and myringotomy were randomly assigned to receive inhalation induction with either isoflurane or halothane and nitrous oxide in oxygen (60/40) via a facemask. Tracheal intubation was performed without any muscle relaxant. Anaesthesia was continued with volatile anaesthetic, adjusted to maintain heart rate and blood pressure within ± 20% of initial values. Our objective was to compare the recovery characteristics of isoflurane and halothane for anaesthesia in the age group of children between 1-3 years. Recovery was evaluated using a modified Aldrette score, a Pain/Discomfort scale and by measuring recovery end points. Emergence and interaction occurred significantly earlier after isoflurane than halothane though discharge times were similar. More children in the isoflurane group achieved full Aldrette scores within the first 45 min after anaesthesia; although this group suffered more discomfort during the first 10 minutes. The amount of postoperative analgesic administered was higher and the first dose was required earlier in the isoflurane group. Postoperative vomiting was more common with halothane, the side effects in the two groups were otherwise similar in the recovery room and in the ward.

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