Mohammad Naeem Malik, Shahid Nawaz Malik, Mahboob-ur Rahman, Muhammad Afzal.
Association of Dyslipidaemia and Acute Coronary Syndrome in Patients Admitted to CCU, PIMS.
Ann Pak Inst Med Sci Jan ;10(3):155-61.

Objective: To investigate lipid profile in acute coronary syndrome patients admitted to CCU, Shaheed Zulfiqar Ali Bhutto medical university Pakistan Institute of Medical Sciences, Islamabad. Setting and Duration of Study: This descriptive cross sectional study was conducted in CCU, Department of cardiology PIMS from January to December, 2014. Materials and Methods: In present cross sectional study a total of 100 admitted patients with diagnosis of acute coronary syndrome (ACS) were included. In this study we diagnosed ACS on the criteria sketched by the Joint European Society of Cardiology/American College of Cardiology Committee. Information regarding demographics and serum levels of TC, LDL-C, HDL-C, and TG determined within the first 24 hours of admission was recorded. Results: Majority 75 (75%) of the patients in this sample were male and the mean age of the patients was 57.66±11.757 years. The distribution of lipid profile showed that 38.70% patients were hypertensive. Hypercholesterolemia was recorded in 62.64% patients, hypertriglyceridemia in 83.33% patients and LDL was noted higher than normal range in 43.30% patients. The HDL value was lower than normal range in 73.20% patients. The fasting blood sugar level showed that 43.48% patients were diabetic. The comparison on the basis of lipid profile parameters showed that the mean values of all lipid profile parameters were not significantly (P-value > 0.05) different between male and female patients. Conclusion: This much high proportion of dyslipidemia among ACS patients showing a strong association of lipid levels like high LDL and low HDL seems to be important in our setup also. Interestingly there was no significant difference in lipid profile between male and female patients.

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