Faisal Ghani Siddiqui, Nargis Syed Soraya.
An audit of Cholecystectomy specimens.
J Surg Pak Jan ;7(2):18-21.

A study was carried out in the Department of Surgery, Liaquat Medical Hospital, Jamshoro (LMCH), Jamshoro / Hyderabad between February 1993 and January 1996 on 188 patients (148 females and 40 males) with symptomatic gallbladder disease in whom cholecystectomy was performed for symptomatic gall bladder disease. The specimens were subjected to histopathology. The presence of atypical epithelial changes like hyperplasia, dysplasia, metaplasia and carcinoma-in-situ were looked for and recorded. Ffteen patients were diagnosed to have carcinoma gallbladder (Ca GB). In thirteen cases Ca GB was associated with gallstones. In four of the thirteen carcinomas in this series (30.7%), metaplasia and dysplasia were found adjacent to the tumour. Hyperplasia, dysplasia, metaplasia and carcinoma-in-situ were found in 32 % of gallbladders removed for gallstones.

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