Javed Iqbal, Munir Ahmad Azhar, Arshad Gardezi.
IgE Mediated Asthma- Effect of Gender on Management.
Ann Pak Inst Med Sci Jan ;10(4):198-202.

Objective: to see the effect of same treatment plan on IgE mediated asthma in different genders. Study Design: Prospective Cohort Study. Place and Duration: The study was conducted at pulmonology outdoor clinic at Bahawalpur from 3rd August 2013 to 3rd October 2013. Materials and Methods: All asthmatic patients who consented to be in the study were asked asthma control test questionnaire (ACT) of five components and among them uncontrolled group was included in the history. Serum IgE levels were checked and similar treatment plan was made. Response was seen in males and females separately over two months. Results: A total of 79 patients met criteria of study included 40 (51%) males and 39(49%) females. The IgE levels in males ranges 49 to 3200 IU/ml (mean-1392 + 1167) and in females ranges 34 to 3200 IU/ml (mean- 1293 + 1308). After 2 months of treatment 28 males (70%) were in partially improved group, 12 (30%) were still in poorly controlled group while among females 18 females (46%) improved to partially improved group and 21 (54%) remained in poorly improved group (P < .05) Conclusion: Outcome of treatment after two months in IgE mediated asthmatic females is significantly poor compared to males.

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