Zahoor Ahmed Rana, Qaimuddin Shaikh, Muhammad Shahzad, Arshad Mehmood Malik, Rizwan Arshad Malik, Mehek Irshad Abro.
Clinical Spectrum of Oral Lichen Planus in Hepatitis C Sero-Positive Patients.
Ann Pak Inst Med Sci Jan ;11(3):133-6.

Background: Oral Lichen Planus can occur alone or as part of generalized Lichen Planus. Clinical presentation differs in various associated conditions such as in patients of Hepatitis C sero-positive cases. Objective: The objective of this study was to evaluate the clinical and morphological spectrum of oral Lichen Planus in HCV sero-positive cases. Place and Duration: This cross sectional observational study was conducted at Oral and Maxillofacial Surgery, Department of Dentistry Shaheed Zulfiqar Ali Medical University (PIMS) Islamabad, reported within the period of five years (2008 to 2013). Materials and Methods: A total number of 78 patients of Oral Lichen Planus with seropositivity were included. An assessment was carried out to describe the morphological patterns and sites in these cases. Results: Out of 78 patients enrolled in this study, 62% were males and 38% were females. Mean age of the patients were 39.5 ± 6.4 years. Duration of disease was 1-5 years in 53%, 6-19 years were 24% and remaining 23 % had duration of disease for more than 20 years Buccal mucosa was involved in 52.5%.Patients having lesion at dorsal tongue were 21.7%,lesions at ventral and lateral was seen in 10.2%, gingiva in 8.9% and lower lip was involved in 6.4% of the cases. Further assessment shows that 34.3% patients with buccal mucosa involvement had reticular type of OLP, 24.5% had erosive type and 15.3% had erythematous type lesions. Patients with involvement of dorsal tongue, 10.2% had reticular type lesion, 5.1% had erosive type and 1.2% had erythematous type of lesion. Among patients with ventral and lateral tongue lesions, 5.1% had reticular type, 1.2% had erosive and 1.2% had erythematous lesions. Conclusion: This study indicated the higher prevalence of reticular type of OLP and the most common site of involvement was buccal mucosa in patients of OLP with Hepatitis C seropositivity.

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