Fouzia Hanif, Tehmina Qamar, Kirn-e Muneera.
Association of Body Mass Index, Polycystic Ovarian Syndrome and its Clinical Presentation.
Ann Pak Inst Med Sci Jan ;11(3):129-32.

Objective: To evaluate the relationship between Body Mass index (BMI), Polycystic Ovarian Syndrome (PCOS) and its clinical presentation. Study design: Case and control study. Place and Duration of Study: The study was conducted in Gynecology and Obstetrics department of Railway Hospital, Rawalpindi in collaboration with Department of Biochemistry IIMC, Rawalpindi from Oct, 2014 to April, 2015. Materials and Methods: Young, unmarried females (n=200) of 16-25 years were enrolled with their written consent in this study., 100 apparently healthy females and 100 diagnosed patients of polycystic ovarian syndrome selected according to Rotterdam criteria. Medical causes including cushing syndrome, androgen secreting tumor, thyroid disorders, prolactinemia. Results: Data was collected on pre-designed questionnaire for age, genetic history of PCOS, age of menarche, history of any medical disorders and medication. The Data was subjected to SPSS version 21 and analyzed using independent T-test and chi square test. Results: 80% of patients suffering from PCOS were obese or overweight. Distribution of clinical symptoms was higher in obese patients as compared to normal weight patients. Conclusion: There is significant relationship between obesity, PCOS and distribution of clinical symptoms in ladies of reproductive age. So ladies of this age group should have normal weight.

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