Faisal Irshad, Hina Mawani, Sana Naz.
Allium sativum essential oil (ASEO); effect of supplementation on serum triglycerides, total cholesterol, HDLC, LDLC and blood cell counts in albino rats.
Professional Med J Jan ;24(4):612-6.

Objectives: To determine the effects of Allium sativum essential oil (ASEO) phytotherapy on serum triglycerides, total cholesterol, HDLc, LDLc and blood cell counts in albino rat model. Study design: Experimental study. Setting and Duration: Animal House, Sindh Agriculture University and Isra University Hyderabad from May 2014 to January 2015. Materials and Methods: 60 albino rats were divided into four groups. Controls were given Placebo. Experimental rat groups were given ASEO 100 mg/kg, 200 mg/kg and 300 mg/kg orally for 30 days. Cardiac puncture was performed for blood sampling. Research variables were analyzed on Statistix 10.0 (USA). Results: Blood lipids showed significant reduction in various blood lipid fractions. Serum LDLc exhibited with a concomitant rise in serum HDLc (p =0.0001) in high ASEO treated rats. Red blood cells, white blood cells and platelet showed significant improvement ASEO fed rats (p=0.001). Conclusion: Allium sativum essential oil (ASEO) phytotherapy showed a rise in HDLc and a reduction in LDLc, triglycerides and total cholesterol with improvement in red blood cell counts.

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