Shaghufta Shafi, Masood Hussain Rao, Sana Rehman.
Orthostatic Hypertension in Patients with Type 2 Diabetes.
Med Forum Jan ;2(5):60-3.

Objective: to compare the frequency of orthostatic hypertension in type 2 diabetic and non diabetic patients. Study Design: A cross sectional comparative study Place and Duration of Study: This study was conducted in a private tertiary care hospital of Karachi in 2011. Materials and Methods: The patients suffering with type 2 diabetics were taken as cases and non diabetic patients as control with age and sex matched in a ratio of 2:1. After taking inform consent socio demographic data of the participants were recorded on a pre structured questionnaire. The findings of SBP and DBP were taken in sitting, supine and standing position. Blood samples were taken with fasting to test HbA1c, total cholesterol, HDL cholesterol, triglyceride and creatinine. Results: Over all 250 diabetic types 2 patients and 125 non diabetic patients were included in the study. The orthostatic hypertension was higher in normotensive type 2 diabetic patients as compared to non-diabetics (16.9% vs. 2.8%, p<0.01). However it was not found statistically significant in hypertensive cases of both the groups. Orthostatic induces a mean increase in SBP and DBP in type 2 diabetic as compared to non diabetics. Serum triglyceride level was also found higher in OHT diabetic patients as compared to non diabetic patients. Conclusion: Orthostatic hypertension is a complication in normotensive diabetic patients as compared to non diabetic patients and it may associate with early stage of neuropathy. It can cause sustained hypertension and other complications. So physicians treating type 2 diabetic patients should take care of it.

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