Mehvish Vakil, Tazeen Mustanser, Naseem Ahmed Shaikh, Salik Rasool, Talat Mirza, Anwar Ali.
Magnitude of Breast Diseases in OJHA Histopathology Department.
Med Forum Jan ;2(6):21-5.

Objective: This study evaluates the current status regarding spectrum of breast diseases from the data record of Dow Diagnostic Research and Reference Laboratory (DDRRL), Karachi. Study Design: Descriptive study. Place and Duration of Study: This study was carried out on obtaining Data of various breast diseases was obtained from the histopathology department of Dow Diagnostic Research and Reference Laboratory (DDRRL), OJAH campus located in Karachi from October 2011 till December 2011. Patients and Methods: Ten months data of 2011 consisted of 829 cases of breast diseases. The diseases were grouped into malignant, benign and inflammatory types. There was no limitation of age and both genders were considered. Cancers other than breast diseases were excluded from the study. Reports of missing information were not analyzed. Normal breast tissue was as well excluded. Results: Analysis revealed 413 as malignant lesions, 322 benign and 80 inflammatory .In malignant tumours invasive ductal carcinoma grade 2 was (23.7%). Fibroadenoma (28.0%) ,fibrocystic change (6.1%), benign phylloides (2.4%), lipoma was 1.2% and no record of lactating adenoma was found. Inflammatory lesion breast abscess (4.0%), chronic mastitis (1.7%) ,granulomatous mastitis (1.7%), duct ectasia (1.3%) and fat necrosis was least diagnosed. Conclusion: Breast diseases trend in the women of Karachi are changing. Malignant breast lesions are presenting at younger age and its occurrence is more than benign and inflammatory lesion altogether in this study.

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