Shahzad Alam Khan, Shahnawaz Hassan, Humayun Riaz Khan, Sohail Safdar.
Acute Kidney Injury; Frequency In Hospitalized Patients.
Professional Med J Jan ;24(10):1510-4.

Objectives: To determine the frequency of acute kidney injury in hospitalized patients at Nishtar hospital, Multan. Study Design: Cross sectional study. Setting: Medical Unit-IV, Nishtar Hospital, Multan. Duration: Duration of study was 6 months from 17/07/2015 to 16/01/2016. Material and Methods: This study involved 383 patients of either sex aged between 37-60 years admitted to medical ward for various medical conditions. Results: The mean age of the patients was 48.96±7.24 years. There were 198 (51.7%) male and 185 (48.3%) female patients in the study group. The most frequent underlying cause requiring hospital admission was a respiratory tract disease observed in 153 (39.9%) patients. AKI was observed in 104 (27.2%) patients. When stratified the frequency of AKI increased significantly with increasing age of the patient; 37-42 years vs. 43-48 years vs. 49-54 years vs. 55-60 years (17.3% vs. 22.7% vs. 26.2% vs. 42.0%; p=.001). It was also significantly (p=.000) higher in patients with diabetes (47.4%) and hepatobiliary disease (34.7%) at admission followed by infections (26.4%) and respiratory tract diseases (17.6%). However, there was no significant difference in the frequency of AKI across genders; male vs. female (25.8% vs. 28.6%; p=.525). Conclusion: Very high frequency of acute kidney injury was observed in our study. Acute kidney injury was significantly associated with increasing age particularly more than 50 years and underlying medical conditions with particular reference to the diabetes mellitus and hepatobiliary diseases. Serial renal parameters monitoring should be adopted for early diagnosis followed by timely management of acute kidney disease. It will decrease associated disease morbidities and mortalities and will also improve quality of life of these patients.

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