Shazia Majid Khan, Farhat Yasmeen, Abida Riaz.
ENDOMETRIAL CARCINOMA; Incidence in women with abnormal uterine bleeding.
Professional Med J Jan ;22(10):1256-61.

Bleeding from the reproductive tract in women is a naturally occurring event, generally the result of menstruation and childbirth, and is not associated with a bleeding disorder in most cases. Dysfunctional uterine bleeding is the most common reason for women to undergo an interventional gynecologic procedure. The major task of the clinician is to exclude endometrial carcinoma in women and to identify organic pathology in order to manage it effectively. Objective. To determine the incidence of endometrial carcinoma in women with abnormal uterine bleeding. Study Design: Cross sectional study. Setting. Department of Obstetrics and Gynecology, Sheikh Zayed Hospital, Rahim Yar Khan. Duration of study: Six months (16th February 2013 to 15th August 2013). Material and method: One hundred and sixteen women with complaint of abnormal uterine bleeding, meeting the inclusion criteria were selected. All the patients were undergone endometrial sampling and assessment of endometrial thickness was done which was confirmed by endometrial biopsy to evaluate endometrial pathologies. The collected data was noted on pre-designed proforma. Results: The mean age was 42.07 years. According to parity, 56 women (48.2%) have 1-4 parity, 48 women (41.4%) have 5-8 parity and 12 women (10.4%) have 9-14 parity. The mean duration of dysfunctional uterine bleeding was 14.64±7.87 months. Six women (5.2%) have endometrial carcinoma while 110 women (94.8%) have no endometrial carcinoma. Conclusion: This study thus proved that in our setup the incidence of endometrial carcinoma is very high. So every patient with abnormal uterine bleeding should undergo endometrial biopsy to rule out endometrial carcinoma.

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