Kausar R, Kausar S, Chiragh S.
In Virto Antifungal Activity Of Aloe Vera And Cymbopogon Citratus Against Candida Albicans.
Biomedica Jan ;33(1):1-3.

Background and Objectives: Efficacy of antifungal agents is limited by incomplete eradication and toxicity, demonstrating need to investigate better agents. The present study was designed to determine the antifungal activity of Aloe vera and Cymbopogon citratus extracts against Candida albicans and to compare their antifungal effect with that of terbinafine and with each other. Methods: Clinically diagnosed and confirmed cases of cutaneous candidiasis were selected. Specimens of skin scraping were taken from each individual and were inoculated on Sabouraud dextrose agar for seven days. Yeast was sub cultured on three Petri dishes to assess the antifungal activity of extracts of Aloe vera, Cymbopogon citratus and terbinafine by disc diffusion method. Results: Mean zone of inhibition was 14.6 ± 1.59 mm (100%) with terbinafine, 9.6 ± 0.43 mm (66%) with Aloe vera and 6.87 ± 0.8 mm (47%) with Cymbopogon citratus. Statistically the difference in zone of inhibition of terbinafine, Aloe vera and Cymbopogon citratus was highly significant (p-value = 0.000). Conclusion: Taking antifungal activity of terbinafine as 100%, it was 66% with Aloe vera and 47% with Cymbopogon citratus which are considered intermediate.

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