Syed Imran Hasan, Ashar Afaq, Mehmood Hussain, Amna Arsalan, Moin Khan, Qaiser Ali Baig.
Arginine-An Instant Relief For Dentinal Hypersensitivity.
Pak Oral Dental J Jan ;37(1):92-5.

The aim of this study was to assess the instant relief of dentinal sensitivity by application of toothpaste containing 8% Arginine CaCO3 compound in patients visiting the Department of Periodontology, Hamdard University Dental Hospital. One hundred patients (38 males and 62 females) with age range from 23 to 65 years having history of dentine hypersensitivity were included in this study by random sampling technique. The consent was taken from the patients and dentinal hypersensitivity was evaluated according to the Visual Analog Scale (VAS) index. DH was evaluated by air-blast stimulus. The response of the patient was recorded immediately at the time of air blast. The DH was measured with the help of Visual Analogue Scale (VAS).Then Arginine – CaCO3 was applied with finger on teeth where DH was reported. After one minute DH was measured by using VAS and readings were calculated. After getting data from all selected patients, results were obtained by using SPSS version 16. Out of hundred patients, 25 patients (25%) were reported to had mild sensitivity and out of 25 patients 12(48%) had instant relief from sensitivity. Thirty five (35%) patients had moderate sensitivity and out of 35 patients, 05(14.28%) observed instant relief from DH whereas 40(40%) patients had severe sensitivity and out of 40 patients only 01(2.5%) had instant relief from DH. The results were statistically analyzed, and it was found that Arginine-CaCO3 application markedly decreases the dentinal sensitivity in majority of patients. It is concluded that patients who were having mild DH had more effect in reduction of DH followed moderate and least effect is observed in the patients with severe DH.

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