Numra Khalid, Alia Ahmed, Iffat Raza, Warda Khalid.
Post-operative pain after use of intra-canal corticosteroid in root canal treatment of vital teeth.
Pak Oral Dental J Jan ;36(2):327-30.

Endodontic therapy carried out on vital pulps is associated with an increased incidence and intensity of pain. Various intra-canal medicaments are proposed to reduce post-operative pain after Root canal treatment. The objective of the study was to determine the frequency of post-operative pain after use of intra-canal dexamethasone in root canal treatment of vital teeth when compared with the Prednisolone. One hundred and twenty patients (with age range between 18-50 years) were randomly divide into two equal group. One group received Decadron (dexamethasone 4mg/ml) intravenous solution as intra-canal medicament, and the 2nd group received prednisolone acetate solution 2.5% in aqueous suspension obtained as commercial preparation. After 24 hours Post-operative pain was marked on Visual Analog Scale. There was statistically significant difference (p<0.05) between dexamethasone and prednisolone groups, with dexamethasone being more effective in reducing post-operative pain.

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