Zubair M, Azmina Hussain, Afsheen Maqsood.
Temperature difference of local anesthesia and its effects on injection pain: a double blinded randomized clinical trial.
Pak Oral Dental J Jan ;36(2):214-6.

Objective of the study were to assess the difference between pain perception of two different temperature anesthesia when injected at two different sites in a split mouth technique. It was a double blinded randomized clinical trial. All the participants and one researcher were kept blinded throughout the research. For this study 50 volunteers were selected by systematic random sampling method from 150 dental volunteers. It is a split mouth technique in which two different sites were randomly selected for anesthetic procedure. Different temperature anesthesias were injected at buccal sulcui using infiltration technique. All volunteers were asked for pain perception at the injected site by using visual analogue scoring scale (VAS). The data were collected and analyzed using SPSS (version 16), cross tabulation was done in order to differentiate the pain perception on injecting local anesthesia at two different temperature. The participants who received warm local anesthetic injection at one site perceived less pain as compared to the other site where anesthesia was injected at room temperature. The present study concluded that warming local anesthesia at 42°C reduces pain perception as compared to the anesthetic injection at room temperature 22°C.

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