Mohammad Shoaib Khan, Abeerah Naseer Khan, Maham Amin, Zeenat Shaheen, Tahmina Roze, Anam Ajmal, Shafi Ullah.
The Association of Malarial Parasites with Platelet Count in Our Population.
Ann Pak Inst Med Sci Jan ;13(2):149-54.

Objective: The present study was designed to assess the association of malarial parasite positive cases with platelets count in our population. Place and Duration: This multicenter study was conducted in Islamabad, Rawalpindi, Peshawar and Dera Ismail Khan from October 2015 to September 2016. Methodology: In this Cross Sectional Descriptive study, total of 500 malaria positive cases were included. Out of which, (100) each from Islamabad, Rawalpindi, and Deera Ismail Khan, while (200) from Peshawar. Blood samples were taken and analyzed through standard procedures. The data obtained was analyzed through SPS version 16. Results: Out of 500 malarial positive cases, 444((88.8%) were infected with Plasmodium vivax, 45(9.0%) by Plasmodium Falciparum, with an average platelet count of 151 ×10^9/L and 143×10^9/L respectively. Cases infected with both Plasmodium Vivax and Plasmodium Falciparum came out to be 11(2.2%) with an average of 145×10^9/L platelets. During the present study, no case of Plasmodium Malariae and Plasmodium Ovale were observed. Gametocyte form in both plasmodium Vivax and Falciparum, caused most cases of thrombocytopenia while Ring form did not affect much. Conclusion: The results of our study showed that infection with Plasmodium Vivax does not grossly affect the average platelet count, while Plasmodium Falciparum causes a mild decrease in the platelet count. Similarly, the infection with both Plasmodium Vivax and Plasmodium Falciparum (mixed type) causes mild thrombocytopenia.

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