Madeeha Nazar, Rahila Aamir, Mohammad Umar, Hamza Abid, Amina Jamil.
Diagnostic Accuracy of Endoscopic Ultrasound and Endoscopic Ultrasound Guided Fine Needle Aspiration in The Diagnosis of Tuberculous Mediastinal Lymphadenopathy.
Ann Pak Inst Med Sci Jan ;13(1):43-6.

Objective: To determine diagnostic accuracy of Endoscopic Ultrasound (EUS) for diagnosis of Tuberculous Mediastinal Lymphadenitis. Methodology: A cross sectional study conducted in a period of six months at the Gastroenterology and Hepatology Department of Holy Family Hospital. 97 patients with radiographic finding of mediastinal lymphadenopathy were selected for EUS. During the procedure aspiration biopsy of significant lymph nodes was done. The diagnosis was made on the basis of specific EUS findings and histopathology report of mediastinal lymph nodes (ML). Results: Age range of patients was 14 years (youngest) to 80 years (oldest). Out of 97 patients 49(50.5%) were males and 48(49.5%) were females. On analysis of data it was found that sensitivity of the EUS was 82.9% and specificity as 58%. Hence it was also calculated that the diagnostic accuracy of the procedure was found to be 70%. Conclusion: This study suggests that EUS is a useful minimally invasive procedure that can be used to provide strong supportive evidence for the diagnosis of tuberculous lymphadenitis involving the mediastinum. In addition, it also suggests that in patients with no positive finding suggestive of Tuberculosis other diagnosis should be considered and further work up should be done.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com