Abdul Rehman Siyal, Rabia Nizar Ali Khoja, Hemandas.
Determination of Clinical Presentations and Risk Factors of Neonatal Hyperbilirubinemia.
Ann Pak Inst Med Sci Jan ;13(1):35-8.

Objective: Assessment of the clinical presentations and risk factors of neonatal hyperbilirubinemia at the paediatrics department of tertiary care Hospital. Study Design: This was a cross-sectional study Place and Duration: At paediatrics department of Liaquat University Hospital Hyderabad, from January 2013 to November 2013. Methodology: Total 114 cases of Hyperbilirubinemia less than 28 days admitted in the neonatal Unit were selected for the study. After admission all the routine laboratory investigations including detailed history of jaundice & duration, serum Bilirubin (direct, indirect), urine C/S, ultrasound Abdomen and X-ray chest were carried out. All the data regarding clinical features and causes of the hyperbilirubinemia was recorded in the proforma. Results: In this study male were found in the majority 67.54%. 65.78% were term and 34.22% were pre term. Jaundice/ yellow discoloration of skin was the most common in 75% of the cases following by fever and refusal to feed 25.43%, and 21.42 respectively. In this study most common risk factor was the sepsis 46.69%, following by birth asphyxia was in 11.40%, hypoglycemia 11.40%, hypothermia 07.89% and hypoalbuminemia was found in 0.87% cases and in 9. 64% cases risk factors were unknown. Conclusion: We concluded that male gender was mostly effected by Hyperbilirubinemia, Jaundice/ yellow discoloration of skin was the most common clinical presentation and neonatal sepsis is the commonest risk factor.

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