Maqbool H Jafary.
Renoprotective benefits of Renin-Angiotensin System inhibition: What is the evidence?.
Pak J Med Sci Jan ;18(4):311-5.

Renin-angiotensin-System (RAS) plays a central role in the pathogenesis and progression of end-organ damage. There is an overwhelming evidence that inhibition of RAS with ACEIs and ARBs results in slowing the progression of renal dysfunction and also a reversal of proteinuria in a significant number of patients with diabets. Ths expectation is that it will positively contribute towards reduction of morbidity and mortality from renal disease. ARBs, which are relatively recent mode of RAS inhibitors, hold a better promise as these are better tolerated that ACEs and may afford better compliance over longer term. This is a review article.

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