Muhammad Ikram, Shad Muhammad, Akhtar Ali, Noor Muhammad, Khan Bahadur, Mian Iftikhar-ul Haq.
Frequency Of Histopathological Patterns Of Renal Disease In A Tertiary Care Hospital.
J Postgrad Med Inst Jan ;31(2):131-4.

Objective: To find out the histological patterns of renal diseases in patients, who underwent renal biopsy at Lady Reading Hospital Peshawar, Pakistan. Methodology: This was a descriptive study conducted at Lady Reading Hospital Peshawar, Pakistan from July 2012 to July 2015. We performed renal biopsy of all patients who presented with; nephrotic syndrome, non-nephrotic range significant proteinuria, rapidly progressive glomerulonephritis, acute unexplained renal failure, sub-acute renal failure of unknown cause and nephritic syndrome. Results: Total number of patients were 200. Mean age was 42.5 ±8.2 yrs. In 56(28%) of the patients the histological diagnosis was focal segmental glomerulosclerosis (FSGS), followed by membranous nephropathy (MN) 28(14%) minimal change disease (MCD) 25(12.5%), membrano-proliferative glomerulonephritis (MPGN) 20(10%) and lupus nephritis in 14(7%). Conclusion: Focal segmental glomerulosclerosis was leading cause of primary glomerular diseases. While secondary glomerular disease (SGN) in our population was most commonly caused by lupus nephritis (LN).

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