Asifullah, Javaid-ur Rehman, Asfandiyar Khan.
Frequency And Complications Of Ischemic Mitral Regurgitation In Patients With Acute Coronary Syndrome.
J Postgrad Med Inst Jan ;31(3):267-70.

Objective: To determine the frequency of ischemic mitral regurgitation, determine severity and defining its complications among patients with acute myocardial infarction (MI). Methodology: This study was conducted at Hayatabad Medical complex. Our study was descriptive cross sectional study in which 262 patients with acute MI were studied using non-probability consecutive sampling technique. Complications were followed for 6 Months & recorded on a pre-designed proforma. Results: In this study mean age was 60 ±1.26 years. One hundred and ten (42%) patients were male while 152(58%) patients were female. One hundred thirty six patients (52%) patients were ST elevation MI (STEMI) and 126(48%) patients were non-ST elevation MI (NSTEMI). Mitral regurgitation was found in 141(54%) patients in whom 104(74%) patients were found to have mild mitral regurgitation, 29(20%) patients were found to have moderate mitral regurgitation and 8(6%) patients were having severe mitral regurgitation. Moreover 25(18%) patients had new onset atrial fibrillation, 24(17%) patients had in-hospital mortality and 15(11%) patients were re-admission with heart failure. Conclusion: Following myocardial infarction, baseline mitral regurgitant severity is associated with deterioration of LV function & increased mortality. The presence of mitral regurgitation confers poor prognosis in patients with acute coronary syndrome.

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