Talha Mahmud, Muhammad Saqib, Muhammad Aasim.
Transbronchial lung biopsy: two years experience of a tertiary care centre.
J Postgrad Med Inst Jan ;32(1):44-8.

Objective: To determine the outcome and safety of transbronchial lung biopsy (TBLB) in various pulmonary disorders. Methodology: This study was carried out at the Department of Pulmonology, Shaikh Zayed Hospital, Federal Postgraduate Medical Institute (FPGMI) Lahore, Pakistan. It was a case series consisting of 50 TBLB procedures conducted via flexible fibreoptic bronchoscope (among >200 diagnostic and therapeutic bronchoscopic procedures) over 24 months (April 2015 to April 2017). The data were entered and analyzed by using SPSS version 20.0. Results: Fifty TBLB procedures yielded results in 45 patients (90%), while 5 (10%) remained inconclusive. Among all patients, pulmonary sarcoidosis was diagnosed in 12 (24%), malignant disease in 9 (18%), pulmonary tuberculosis (PTB) in 5 (10%), chronic hypersensitivity pneumonitis (CHP) in 4 (8%), orga- nizing pneumonia (OP) in 3 (6%), slowly resolving bacterial pneumonia in 5 (10%), non-specific interstitial pneumonia (NSIP) in 4 (8%) and others in 3(6%) of patients. Per procedural bleeding after TBLB occurred in around 13 (30%) but none developed a pneumothorax, hemodynamic instability or death during the procedure. Conclusion: TBLB is a safe bronchoscopic procedure and carries a high diagnostic yield in disorders involving the pulmonary parenchyma.

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