Jai Kirshin, Sameena Afghan, Aqeela Ayub, Kishor Shah, Maqbool Hussain.
Clinical Outcome of Measles and Rubella with Maculopapular Rash At Children's Hospital, Pims, Islamabad.
Pak J Public Health Jan ;6(4):26-30.

BACKGROUND: Measles is highly endemic disease in Pakistan that can be prevented by vaccinating the child.Patients with rash and fever are the major syptoms of this infection. The aim of this study was to find the associationof clinical and serological outcome of measles and rubella with demographic profiles in patients hospitalised withclinical suspicion of these conditions. METHODS: A descriptive cross sectional study was conducted in children hospital of PIMS Islamabad where allchildren presenting with maculopapular rash in outdoor patient, indoor patient and accident and emergencydepartment were enrolled. The study duration was one year or the completion of required sample size. A total of 73children who fulfilled the inclusion criteria were enrolled in this study. A purposive sampling technique was used toselect cases. Data was collected through a structured proforma especially designed for this study. Permission wastaken from the Hospital Ethical Committee before the commencement of the study. A written consent was also takenfrom the parents of children prior to conduct the study. RESULTS: All the children in this study was 46.5 (± 40.1) months of age, the mean (SD) age was 4 years and 10months (± 3 years and 4 months). The median age of all children was 24 months (2 years). The youngest child was 7months old while the eldest child was 12 years (144 months) of age. Out of 73 children enrolled in the current studywho presented with maculopapular rash and their serological outcome was assessed, 50 (68.5 percent) were boyswhereas 23 (31.5 percent) were girls. Koplik's spots were present among 56 (76.7 percent) children whereas 17(23.3 percent) did not have Koplik's spots at the time of enrolment. lymphadenopathy was assessed in 35 (47.9percent) children while 38 (52.1 percent) did not have lymphadenopathy at the time of enrolment. CONCLUSION: Study concluded that a higher proportion of children presenting with maculopapular rash werediagnosed to have measles on the basis of serology.

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