Hina Kokab, Nudrat Elahi, Tabassum Shaheen.
Pregnancy associated with Fibroids: Complications and Pregnancy outcome.
J Coll Physicians Surg Pak Jan ;12(12):731-4.

Objective: To assess the outcome of pregnancies in women with uterine fibroids. Design: A prospective comparative study. Place and Duration of Study: Department of Obstetrics and Gynaecology Unit-I, Nishtar Hospital, Multan from December, 1994 to December, 1996. Subjects and Methods: Our study consisted of 32 pregnant women with uterine fibroids and our control group comprised of 100 randomly selected pregnant women with a normal uterus. We compared age, parity, pregnancy and labour complications, mode of delivery and indications for caesarean section. Relationship of fibroid with the placenta was also noted. Results: The majority of women in the two groups belonged to the age group between 25-35 years. Women in the study group were mostly nulliparous than controls (56.25% vs 12%). The complications of Pre-mature rupture of membrane (PROM), pre-term labour, Intra-uterine growth restriction (IUGR), antepartum and postpartum haemorrhage were not quite different in the two groups. The spontaneous pregnancy loss rate was twice than in the controls (12.5% vs 6%). The rate of caesarean section was also higher among women with uterine fibroids (40.62% vs 23%) and the occurrence of breech presentation was also increased (38.46% vs 13%). Retroplacental myoma was found in 9.375% of the cases. Conclusion: Although uterine fibroids are associated with an increased risk of abortions and caesarean section, the results of other pregnancy associated complications in our patients with uterine fibroids is encouraging.

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