Zaheer S, Naseem N, Nagi AH.
Relative Frequency of Odontogenic Lesions Based on Their Histological Diagnosis.
Biomedica Jan ;33(3):234-8.

Background and Objective: Odontogenic cysts and ameloblastomas are the most commonly occurring lesions arising from odontogenic epithelium in the oral cavity. Clinical and radiographical findings have their limitations in correctly diagnosing these lesions which may significantly affect the treatment and prognosis of patients. Hence, histological diagnosis along with their classification is mandatory in these cases. This study was designed to see the relative frequency of histologically diagnosed odontogenic lesions in comparison to their provisional clinical diagnosis. Methods: A total of 114 blocks containing odontogenic lesions along with their clinical records were acquired from Morbid Anatomy and Histopathology department at University of Health Sciences Lahore and a local private laboratory from year 2011 ? 2015. Hematoxylin and Eosin staining was performed on section for final diagnosis. Results: In a total of 114 patients, 32 (28.02%) differed in their initial clinical and final histological diagnosis. From a total of 32 lesions, 4 unicystic ameloblastomas were provisionally diagnosed as dentigerous cysts, 8 OKCs were provisionally diagnosed as multicystic ameloblastoma, 7 dentigerous cysts were provisionally diagnosed as radicular cysts, 4 OKCs were provisionally diagnosed as dentigerous cysts and 9 ameloblastomas were provisionally diagnosed as OKCs. Conclusion: Owing to the propensity for misdiagnosis, all the cystic lesions from the oral cavity should be sent to the laboratory for their final diagnosis for better treatment and prognosis in these patients.

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