Adnan Mehraj, Bashir-ur Rehman, Masood-ur Rehman, Abid Hussain Dar, Zubina Adnan, Misha Anis, Sara Bashir, Anam Altaf.
Gender based Outcome of Acute Cholecystitis.
J Surg Pak Jan ;22(1):8-11.

Objective: To find out whether or not male gender is associated with more severe gallbladder inflammation. Study design: Retrospective review of records. Place & Duration of study: Sheikh Khalifa Bin Zayed Al Nahyan (SKBZ) Hospital / CMH Muzaffarabad, from January 2012 to June 2015. Methodology: A retrospective data analysis of patients who underwent laparoscopic cholecystectomy for acute cholecystitis was done. Data for 740 patients with cholecystitis was retrieved. Out of these 220 patients who had laparoscopic cholecystectomy within 72 hours of admission, were included in the study. Gallbladder inflammation was confirmed on histopathology report. Results: There were 110 male and 110 female patients in this series. There was a significant number of male patients who had severe gallbladder inflammation in comparison with female patients (p=0.002). The male gender was confirmed in a multivariate analysis as an independent risk factor for severe cholecystits (p=0.018). Conclusions: Male gender is a risk factor for severe gall bladder inflammation. Early surgical intervention is therefore warranted to prevent complications.

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