Ainul Hadi, Syed Nadeem Ali Shah, Farrukh Ozair Shah, Hikmatullah Qureshi, Saadia Muhammad.
Postoperative Outcome of Early Laparoscopic and Open Cholecystectomy for Acute Calculous Cholecystitis.
J Surg Pak Jan ;21(2):49-53.

Objective: To assess the optimal timing of intervention and post operative morbidity for acute calculous cholecystitis. Study design: Cross sectional study. Place & Duration of study: Surgical unit Hayatabad Medical Complex Peshawar, from February 2015 to January 2016. Methodology: A total of 110 patients having age range of 20-55 year were included. Patients having common bile duct stones, clinically jaundiced and associated co morbid diseases, were excluded. Patients were divided into two groups having 55 patients in each group. Group A patients underwent early laparoscopic / open cholecystectomy within 72 hours of presentation while group B patients had delayed laparoscopic / open cholecystectomy after 72 hours of presentation. In both the groups laparoscopic cholecystectomy was attempted initially but in difficult cases decision was made to convert to open procedure. Postoperative morbidity of both groups was compared. Results: Mean age of the study population was 40.5+2.5 year. Male to female ratio was 1: 8.2. Biliary leak occurred in 1.8% patients in group A and 5.5% in group B. Common bile duct injuries occurred in 1.8% versus 3.6% patients and conversion rate was 3.6% against 12.7% in group A and group B respectively. Hospital stay in group A patients was 2.5 days as compared to 4.5 days in group B. Overall complication rate was 7.2% and 29.1% for groups A and B. Conclusion: Early laparoscopic cholecystectomy within 72 hours significantly decreased the conversion rate, postoperative morbidity and the length of hospital stay.

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