Urooj Naz, Shazia Naseeb, Samia Shuja.
Concordance Between Visual Inspection with Acetic Acid Test and Pap Smear in Detection of Cervical Cancer.
J Surg Pak Jan ;21(1):18-22.

Objective: To determine the agreement between visual inspection with acetic acid test (VIT) and Pap smear in detection of cervical cancer. Study design: Cross-sectional study. Place & Duration of study: Department of Obstetrics and Gynaecology Unit-II, Jinnah Postgraduate Medical Centre Karachi, from March 2013 to April 2014. Methodology: Attendants of the patients visiting antenatal clinic were included in this study. VIA test was performed by the application of 05% acetic acid on the cervix through cotton tipped applicator. After 5 minutes a naked-eye assessment was performed under direct illumination of a 100-watt halogen lamp. A positive visual inspection with acetic acid test was defined as opaque, acetowhite lesions with raised surface and well defined margins present on the cervix. The Pap smear sample was obtained by conventional method and fixed with 95% ethanol for 30 minutes before sending to the laboratory for reporting. Results: A total of 217 patients were selected. Positive agreement between VIA test and Pap smear was found in 158 (72.8%) cases. Agreement was also cross checked with cervical cancer risk factors like age, parity, literacy and socio-economical status. Mean age of the study participants was 34.46 year. Majority (n=89 - 41%) of the women were illiterate, belonged to the poor socioeconomic class (n=52 - 24.1%) and multipara (n=149 - 68.6%). Conclusion: Overall agreement of similar results between VIA test and Pap smear was found in majority of the patients.

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