Mazhar Iqbal, Mariam Malik, Sughra Perveen.
Morbidity and Mortality in Acute Pancreatitis.
J Surg Pak Jan ;20(4):128-32.

Objective: To determine the morbidity, mortality and causes of acute pancreatitis in patients presenting to a tertiary care hospital. Study design: Descriptive case series. Place & Duration of study: Department of Surgery Ward 3 Jinnah Postgraduate Medical Centre Karachi, from October 2013 to October 2015. Methodology: Patients diagnosed as having acute pancreatitis were included in the study. Laboratory and radiological investigation were carried out. Local, systemic complications, mortality and causes of acute pancreatitis were noted. Patients were followed up to 3 months to record the late complication of acute pancreatitis. Results: A total of 220 patients of acute pancreatitis were included. Average age of patients was 43 year. There were 150 (68.18%) female and 70 (31.82%) male patients. Of the total 176 (80%) patients had acute mild pancreatitis, 24 (10.90%) acute moderate pancreatitis and 20 (9.10%) acute severe pancreatitis. Overall mortality was 3.64% (n=8). Mortality in acute moderate pancreatitis was 8.33% and in acute severe pancreatitis 30%. Local and systemic complications occurred in 18.33% patients. This included ARDS (20%), pleural effusion (20%), hypocalcaemia (20%), shock (18.8%), neurological (13.63%) and renal failure (13.63%). In 85% cases cause of acute pancreatitis was cholelithiasis. Conclusions: Overall mortality in acute pancreatitis was 3.64. It was more in cases of acute severe pancreatitis. The major cause of acute pancreatitis was cholelithiasis.

PakMediNet -Pakistan's largest Database of Pakistani Medical Journals - http://www.pakmedinet.com