Khalid Mehmood, Nabeea Junaid.
Prevalence of undiagnosed type 2 diabetes mellitus in Pakistan: Results of screen-diabetes disease registry.
J Pak Med Assoc Jan ;68(8):1171-8.

Objective: To estimate the prevalence of undiagnosed diabetes in patients visiting the primary care physicians for any reason in urban outpatient settings. Methods: This national, multicentre, non-interventional disease registry was conducted from October 2011 to August 2013 across Sindh and Punjab provinces of Pakistan and comprised randomly selected health centres with qualified general practitioners. Patients aged 45 years or more and willing to have a random blood sugar screening test were selected. They were screened on American Diabetes Association risk factors. Fasting blood glucose and glycated haemoglobin of patients with random blood sugar >200 mg/dL were checked and those with values >126 mg/dL or >6.5% respectively were considered newly-diagnosed type diabetics T2DM. They were followed up three months later. Results: There were 8,250 patients with a mean age of 53.2±8.1 years, and mean body mass index of 27.3±5.3kg/m2. The prevalence of undiagnosed diabetes in patients visiting primary care physicians for any reason was 525(6.4%). Overall, 484(92.2%) of the newly-diagnosed type 2 diabetics were advised lifestyle modification, 460(88.1%) were put on oral anti-diabetic drugs, and insulin was initiated in 50(9.5%) patients. There was a mean decrease of 1.6±1.6%in glycated haemoglobin and 41.9±56.8mg/dL in fasting blood glucose from baseline to the three-month follow-up. Conclusion: The burden of undiagnosed diabetes in Pakistan was found to be considerable. With proper management, significant improvement was shown.

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