Shazia Anwar, Sajjad Ahmad, Irshad Nabi Sandhu, Rana Muhammad Haseeb Kamran, Umair Asghar.
Prevalence Of Hepatitis B And Hepatitis C Infection In Patients Undergoing Coronary Angiography.
J Cardiovascular Dis Jan ;14(2):42-5.

OBEJECTIVES: To determine the prevalence of hepatitis B and C in patients undergoing conventional coronary angiography and compare it between patients with and without significant coroary artery disease (CAD). METHODS: This cross-sectional study was carried out at Mayo Hospital , Lahore from 1st july 2017 to 31st december 2017.All those patients scheduled to have elective coronary angiography within this period were enrolled in the study. Demographic details and detailed clinical history regarding the risk factors of CAD such as smoking, hypertension, diabetes, dyslipidemia or family history of CVD was taken from each patient.Blood sample was drawn in each case for HBV and HCV testing. CAD was defined as ?50% coronary lumen stenosis of any coronary vessel on angiography. RESULTS: A total of 325 patients took part in the study comprising of 185 males and 140 females. The prevalence of HBV and HCV among patients undergoing angiography was found to be 3.4% and 33.8% respectively. HCV serology was positive in 85 (37.8%) patients in the CAD group whereas 25 (25%) patients were HCV positive in patients having no significant CAD (p value = 0.02). Ther prevalence of hepatitis B infection was similar into groups (9(4%) vs 2(2%): p value = 0.36). CONCLUSION: Hepatitis C virus infection was more prevalent than hepatitis B virus infection in patients undergoing coronary angiography. Furthermore, hepatitis C positivity was more in patients with significant CAD as compared to those with no significant CAD. No such difference was observed with hepatitis B positivity.

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