Syed Amjad Hussain Zaidi, Ahsan Ali Mirza, Kashif Jameel, Anam Altaf.
Diagnostic Value of Mean Platelet Volume in Acute Appendicitis.
J Surg Pak Jan ;22(4):114-7.

Objective: To find out diagnostic value of mean platelet volume (MPV) in acute appendicitis. Study design: Case control study. Place & Duration of study: Department of Pathology, Pakistan Atomic Energy Commission General Hospital (PAEC), Islamabad, from June 2012 to November 2012. Methodology: Patients who underwent appendectomy were included. The patients in control group were normal individuals who attended hospital for blood donation. Both groups were followed for four months. Data was collected through pre tested questionnaire. A correlation was applied to find out the relationship between MPV and other variables. Results: A total 140 participants were included in this study with equal number of exposed and unexposed (70 each). There were 66.4% males and 33.6% females in exposed group while 55.4% males and 44.6% females in unexposed group. The mean age was 33.6±11.2 year among exposed while 30.8±10.1 year among unexposed group (p=0.407). Those individuals who underwent acute appendicitis surgery were more likely to have reduction in MPV than those who did not (Odds Ratio 1.21, 95% CI, p<0.001). Conclusions: The patients of acute appendicitis had reduction in mean platelet volume. Mean platelet volume had lower diagnostic value as compared to leukocyte count.

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