Muhammad Rizwan Mahmud, Sadaf Zaman, Nadeem Naseem, Nadeem Iqbal, Nida Tanveer, Mohammad Ali Khalid, Haider Zaigham Baqai.
Comparison of Vitamin D Levels in patients with Dengue Haemorrhagic Fever and Dengue Fever.
J Rawal Med Uni Jan ;22(2):92-5.

Background: To compare vitamin D levels in patients of dengue hemorrhagic fever with dengue fever Methods: A total of 50 patients with diagnosed dengue fever, who fulfilled the inclusion criteria were enrolled in the study. Patients were divided into two groups having 25 participants each; one group had Dengue fever (DF) while the other was suffering from dengue hemorrhagic fever (DHF). Vitamin D was estimated by chemiluminescence method. Pearson?s Chi square was applied to compare the proportion of patients in each study group. Relative Risk was measured along with 95% confidence interval. Significant p- value was < 0.05. Results: Mean age of patients was 37.79 ± 15.2 years (range: 16-90 years). There were 74% males and 26% females. Mean vitamin D levels in dengue fever patients were higher (21.5 ± 13.6 ng/ml) as compared to Dengue hemorrhagic fever (12.4 ± 5.6 ng/ml). Difference was statistically significant (p=0.003). Conclusions: Vitamin D may have a role in management of dengue fever. Low levels of vitamin D might be associated with dengue hemorrhagic fever.

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