Shahzad Nayyar, Kamran Zamurad Malik, Sidra Malik.
Sucralfate - a novel intervention to alleviate post-tonsillectomy odynophagia.
Pak Armed Forces Med J Jan ;68(4):883-86.

Objective:  To evaluate the efficacy of sucralfate for relieving post-tonsillectomy odynophagia. Study Design:  Randomized clinical trial. Place and Duration of study:  This study was carried out at department of ENT, Combined Military Hospital Muzaffarabad for 9 month Feb 2017 to Oct 2017. Material and Methods:  Sixty patients of different age groups were selected randomly and were divided into two groups with equal gender distribution. Both groups underwent tonsillectomy using bipolar diathermy. Standard post-operative antibiotic and analgesic cover was provided. In addition, Group A was prescribed oral sucralfate syrup, post operatively, 3 times a day for 5 days. Patients were inquired about pain after 5 days. Patients in Group A showed better pain relief and the difference was statistically significant. Results:  The mean age of surgery in our study was 13.75 ± 8.12 years. The mean operative time was 16.12 ± 1.33 minutes. About 83.3% patients in group-A achieved satisfactory pain relief as compared to 43%patients in group-B. This difference was statistically significant with a p value of 0.001 Conclusion:  Prescription of sucralfate in patients after tonsillectomy resulted in alleviation of post-operative odynophagia. Hence, we advocate the use of this cost-effective, readily available and safe drug after tonsillectomy.  

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