Rizwan Ahmed, Amir Hussain, Muhammad Zill-e Humayon, Omer Bin Abdul Aziz, Irfan Shuk, Komal Asgher.
Comparison of mean blood loss using harmonic scalpel and monopolar electrocautry in modified radical mastectomy.
Pak Armed Forces Med J Jan ;68(2):221-24.

Objective:The objective of this study was to compare the mean per operative and post operative blood loss using harmonic scalpel and monopolar electrocautry in modified radical mastectomy. Study Design: Randomized controlled trial. Place and Duration of Study: Department of surgery PNS Shifa Karachi, from 25th Oct 2011 to 24th Apr 2012. Material and Methods: A total of 64 patients, undergoing Modified Radical Mastectomy (MRM) were randomly divided into two groups of 32 patients each, using random numbers table. Dissection in group A was done using Harmonic Scalpel (HS). Group B underwent Monopolar Electrocautry (ME) for dissection and hemostasis. Mean per and post operative blood loss was calculated in milliliters. Results: Mean per operative and post operative blood loss using harmonic scalpel (group-A) was 121.19 ± 5.63 ml while 603.35 ± 8.04 ml loss was recorded in monopolar electrocautry group (group B). A p-value was calculated as <0.001 which shows a significant difference between both the groups. Conclusion:The mean per and post operative blood loss using harmonic scalpel is significantly less than using monopolar electrocautry in modified radical mastectomy. Keywords: Modified radical mastectomy, Monopolar electrocautry, ost operative blood loss, Harmonic scalpel. 

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