Sakina Fatima, Muhammad Iyad N, Subia Jamil, Tuba Siddiqui.
Prescribing Practices of Broad Spectrum Antibiotics in Tertiary Care Hospital: an Observational Study.
RADS J Pharm Pharmaceut Sci Jan ;6(1):07-16.

Objective: The present study was designed to investigate the utilization of broad spectrum antibiotics in a tertiary care hospital setup. Methods: The observational study was evaluated 685 in-patients admitted in various wards during three-months period from July-September 2015. After the data collection, it was analyzed for prevalent gender, various age groups, collected specimen, availability of culture sensitivity, Gram-Negative pathogens and prescribing trends of antibiotics alone or in combinations. Results: The results showed that high preponderance of prescribed antibiotics was found in females with age ranges of 16-30 and 31-45 years, whereas in male patients 1-15 and >75 years. The study also revealed that 25% of patients were tested for culture sensitivity and 75% were treated with antibiotics either empirically or prophylactically. The prescribing pattern of antibiotics showed higher rate of utilization of broad spectrum cephalosporins, either alone or in combination with other antibiotics. Conclusion: The study concluded that the utilization of broad spectrum antibiotics such as broad spectrum cephalosporins must be rationale with culture sensitivity test for antibiotic selection in clinical situations and hygienic practices in hospitals must be employed which can reduced the risk of infections. Antibiotic stewardship programs can also have reduced the inappropriate use of antibiotics.

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