Mohammad Mohsin Khan, Mmustafa Ali Siddiqui, Muhammad Irfan Qadir Khan, Arshia Mobeen.
Role of Fine Needle Aspiration Cytology on Abdominal Ultrasonography in the Diagnosis of Hepatobiliary Masses.
Pak J Med Health Sci Jan ;8(1):85-8.

Aim: To compare the diagnostic accuracies of ultrasound guided FNAC and ultrasound alone, considering histopathology as gold standard. Study design: Cross Sectional study. Setting: Histopathology Department, AIMCS, Lahore. Duration of study: One year from July 22, 2012 to August 13, 2013. Methods: Abdominal ultrasound, ultrasound guided FNAC and biopsy of 100 patients with clinical diagnosis of hepatobiliary masses were carried out. Results: Histopathologically, 92 masses were malignant (35 metastatic carcinomas, 53 hepatocellular carcinomas (HCC), 03 gallbladder adenocarcinomas and one cholangiocarcinoma) and 08 were benign abscesses. Ultrasound diagnosed 51 cases as HCC, 35 as metastatic, 03 gallbladder cancers, 01 cholangiocarcinoma and 10 as benign. FNAC revealed 91 malignant (35 metastatic, 52 HCC, 03 gallbladder adenocarcinomas, 01 cholangiocarcinoma) and 09 benign (08 abscesses, and 01 benign hepatocytes only). FNAC accurately diagnosed almost all the cases. Ultrasound correctly diagnosed all gallbladder masses, cholangiocarcinoma, and many abscesses, metastatic tumors and HCC but labeled 02 benign abscesses as necrotic HCC, and 04 necrotic HCC as benign abscesses. Conclusion: FNAC is superior to ultrasound alone in the diagnosis of hepatobiliary masses & with the help of cell block, it can even be used for the typing of tumors.

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